In pathogenesis, there are two critical moments for infective endocarditis development. Firstly, there is the presence of injured or inflamed endocardium, which serves as a substrate for bacterial adhesion. Secondly, bacteremia acts as the initiating factor for infective endocarditis, occurring after irritation or tissue damage that creates a portal of entry for bacteria into the bloodstream.

Unfortunately, bacteremia is not an uncommon event and may even be initiated by everyday routine activities such as tooth brushing and chewing.

The prominent role of oral bacteria in the development of endocarditis—entering the bloodstream as part of routine daily activities, but especially during certain dental procedures—has been the subject of debate for decades.

Undoubtedly, the prevention of infective endocarditis is of immense importance for dental practitioners. However, dentists today face a variety of guidelines and recommendations issued by professional societies and reputable associations, which often differ significantly from country to country.

The aim of the lecture is to compare various recommendations proposed by respected associations and highlight their advantages and disadvantages in accordance with evidence-based data.

Participants will receive a contemporary update on information related to dental procedures that require antibiotic prophylaxis, recommended prophylaxis regimens, the medical conditions that mandate prophylaxis, and how to manage specific situations in which antibiotic prophylaxis is required.